Dr. Jeffrey Weber is Adams Professor of Medicine and Molecular Microbiology and Chief of the Division of Medical Oncology at the Keck School of Medicine of the University of Southern California. He also is the Associate Director for Clinical Research of the USC/Norris Comprehensive Cancer Center.

His interests lie in the field of cancer immunotherapy and vaccine development. Dr. Weber is an experienced clinical trialist and has been funded by the NCI for the last decade to perform clinical immunotherapy trials employing cytokines like Interleukin-12 and novel antibodies against CTLA-4 to demonstrate their clinical utility in combination with vaccines. Recently, anti-PD-1 antibody has also been shown to augment the proliferation and effector activity of tumor antigen-specific T cells. Another interest is the prediction of outcome after immunotherapy or vaccine treatment by analysis of genetic polymorphisms in cytokine and immune regulatory genes. He has also performed adoptive transfer studies using dendritic cells in melanoma patients and has been among the first to test vaccine strategies against human papillomaviruses in patients with HPV-induced high grade cervical dysplasia.