Crystal L. Mackall is Chief of the Immunology Section and Acting Branch Chief of the Pediatric Oncology Branch of the National Cancer Institute. She completed an accelerated 6-year B.S./M.D. program at the Northeastern Ohio Universities College of Medicine in 1984 followed by a combined Internal Medicine/Pediatrics Residency in Akron, Ohio in 1988. She came to the NCI in 1989 as a Clinical Associate in the Pediatric Oncology Branch where she completed her clinical subspecialty training in 1992. She is Board Certified in Internal Medicine, Pediatrics and Pediatric Hematology/Oncology. Dr. Mackall undertook postdoctoral scientific training in the Experimental Immunology Branch from 1990-1996. Since that time she has directed an independent research effort in the Pediatric Oncology Branch. Dr. Mackall has received international recognition for her work on T cell immune reconstitution and she leads an active translational research program which incorporates basic studies in immunobiology with clinical trials of immunotherapy for pediatric cancer. She received an NCI Director's Award for this effort in 2003. In addition, she is particularly dedicated to teaching and mentoring young investigators as evidenced by her receipt of the NIH Distinguished Clinical Teacher Award in 2000 and the NCI Mentor of Merit Award in 2003.